Edward W. Cowen, M.D., M.H.Sc.

Dr. Cowen’s primary interests include chronic graft-versus-host disease (GVHD), primary immunodeficiency, autoinflammatory skin disease, cancer genodermatoses, and adverse drug reactions. Dr. Cowen has authored more than 200 original manuscripts and chapters. Novel discoveries include the first identification of total body irradiation as a risk factor for skin fibrosis in chronic GVHD, and the first comprehensive series describing angiomatosis, calcinosis, and alopecia areata and vitiligo in the cGVHD setting. Current research interests include novel treatments for skin fibrosis and objective measurement tools to assess disease activity and response.

Dr. Cowen also participates in the NIH Undiagnosed Disease program and has been involved in the description of several novel syndromes in collaboration with other NIH investigators, including deficiency of the IL-1 receptor antagonist (DIRA), GATA2 deficiency, ADA2 deficiency, cutaneous skeletal hypophosphatemia syndrome, and SAVI syndrome. Most recently, Dr. Cowen identified onychopapilloma as a novel cutaneous finding in BAP1 tumor predisposition syndrome.